THE PICTET-SPENGLER REACTION UPDATES ITS HABITS

The Pictet-Spengler Reaction Updates Its Habits

The Pictet-Spengler reaction (P-S) is one of the most direct, efficient, and variable synthetic method for the construction of privileged Commercial Grinder pharmacophores such as tetrahydro-isoquinolines (THIQs), tetrahydro-β-carbolines (THBCs), and polyheterocyclic frameworks.In the lustro (five-year period) following its centenary birthday,

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Umbilical acupuncture combined with warm needle acupuncture for the treatment of residual numbness after lumbar disc herniation surgery: a protocol of a randomized controlled trial

BackgroundPostoperative residual numbness following lumbar disc herniation (LDH) surgery is a relatively common symptom.Existing drugs and physical therapies are not very effective.Acupuncture is effective for the treatment of LDH, but there are limited reports on its use for postoperative numbness.Based on clinical observations and literature revi

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Visualisation of sentinel lymph node with indium-based near infrared emitting Quantum Dots in a murine metastatic breast cancer model.

Due to its non-invasiveness, high temporal resolution and lower cost, fluorescence imaging is an interesting alternative to the current method (blue dye and radiocolloid) of sentinel lymph node (SLN) mapping in breast cancer.Near-infrared (NIR) emitting cadmium-based Quantum Dots (QDs) could be used for this purpose; however, their wide application

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